DETAILED NOTES ON LIMITED EDITION EXCLUSIVE LSD CRYSTAL)

From the LSD-certain crystal construction, the aspect chain on the lid residue L209EL2 types extensive hydrophobic contacts with equally LSD and encompassing residues in TMs III, IV, and V (Determine 4C). In the event the lid moved apart to reveal the binding pocket in simulation, several of these contacts broke. We thus hypothesized that L209EL2 f